If you’ve been wondering whether CBD could be a secret weapon for liver health, science seems to be pointing to a resounding ‘yes’.
Recent studies have been exploring how components of cannabis, like CBD and Δ9-THCA, might offer much-needed relief for liver conditions.
One such study revealed that CBD significantly improved brain and liver function in mice suffering from liver failure. Another found that Δ9-THCA reduced liver damage and inflammation.
These findings are backed up by further research indicating that cannabinoids could help in managing chronic liver diseases.
Here’s the exciting part: we’re going to dive into the world of CBD and find out which products might just be the best fit for bolstering your liver health.
So, stick with us, and let’s explore the power of CBD for liver damage together.
Our Process for Selecting the Best CBD for Liver Damage
Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.
Unwavering Quality Standards
Each CBD product that made our list meets these essentials:
- It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
- It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
- It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
- It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.
Delving Deeper into the Details
But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:
- The potency of each product, because when it comes to CBD, the dosage makes a difference.
- The ingredient list: we favored products with ingredients specifically known for stress relief.
- The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
- The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
- A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.
Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.
Why Only Five Products in Our Guide?
In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?
We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.
So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.
So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.
Every product on this list is of the highest quality and offers the best price-per-milligram ratio.
So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.
Best 5 CBD Products Effective for Liver Damage
CBD CBG Morning Capsules For Energy Focus
https://cbdfx.com/products/cbd-cbg-morning-capsules-900mg/
Priced at $65, the CBD CBG Morning Capsules for Energy Focus are made from vegan and 100% organic CBD + CBG oil. The CBD and CBG in these capsules help improve mental and physical calm and promote energy and alertness. The capsules also contain L-Tyrosine, an amino acid known for improving concentration, and Curcumin, a powerful antioxidant known for its anti-inflammatory properties. While it’s not directly designed for liver damage, maintaining overall health can contribute to a healthy liver.
Full Spectrum Calming CBD Gummies
Priced at $110, the Full Spectrum Calming CBD Gummies are designed to help you relax and unwind naturally. These gummies contain 200mg of CBD and 4mg of THC per serving along with soothing herbs like Ashwagandha, Lemon Balm, Chamomile, Valerian, GABA, and L-Theanine. While they do not target liver damage directly, maintaining a relaxed state can help manage stress levels, which could indirectly aid liver health.
Full Spectrum CBD Softgels Sleep PM
https://www.cbdmd.com/collections/cbd-capsules/products/cbd-softgels-sleep-pm?variant=44968933884200
Priced at $50, the Full Spectrum CBD Softgels Sleep PM is a sleep aid that combines CBD+THC with Melatonin and soothing herbs. Good sleep is essential for overall health, including liver function. A well-rested body can better repair and regenerate, which can be beneficial for liver health.
CBDISTILLERY THC-FREE CBD OIL TINCTURE
Priced at $60, the CBDistillery THC-Free CBD Oil Tincture is a 1000mg, 100% all-natural, pesticide-free, and THC-free product. The oil is made from 99% pure hemp CBD isolate, making it a strong option for those seeking the benefits of CBD without the effects of THC. While not directly beneficial for liver damage, CBD has been known for its potential anti-inflammatory and antioxidant properties.
PM Softgel Capsules
https://www.cbdmd.com/collections/cbd-capsules/products/pm-softgel-capsules?variant=45112858968360
Priced at $50, the PM Softgel Capsules are a convenient sleep aid formulated with Superior Broad Spectrum hemp extracts, melatonin, and calming herbs. A good night’s sleep is essential for the body’s natural regeneration process, including the liver. With added levels of CBN, these softgels may help in achieving a relaxed state and better sleep, contributing to overall liver health.
What the Research Says About CBD and Liver Damage
Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057300/
This study investigated the effects of cannabidiol (CBD), a non-psychoactive component of Cannabis sativa, on liver and brain functions in mice suffering from hepatic encephalopathy, a neuropsychiatric disorder resulting from liver failure. The study’s date is not specified.
In the experiment, female mice were given injections to induce liver failure symptoms and then treated with CBD. Their neurological, motor, and cognitive functions, which were severely impaired by induced liver failure, notably improved following CBD administration. Additionally, the CBD treatment normalized increased plasma levels of ammonia, bilirubin, liver enzymes, and serotonin, all of which were elevated due to liver failure. It also moderated astrogliosis (a response to brain damage) in the mice’s brains.
The results suggest that CBD can restore liver function, normalize serotonin levels, and improve brain pathology, contributing to normalized brain function. This implies CBD’s benefits might be due to its combined action on the liver and brain.
Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice
https://pubmed.ncbi.nlm.nih.gov/33341026/
The study tested whether a non-psychoactive substance in cannabis, called Δ9-THCA, could help treat liver issues. The scientists used cell lines and mice to conduct the experiments. They gave some mice a chemical or a high-fat diet to induce liver disease and then treated them with Δ9-THCA.
The research showed that Δ9-THCA could lessen liver fibrosis, a form of liver damage, and inflammation. It also decreased the number of certain immune cells in the liver. In overweight mice with fatty liver disease and severe liver damage, Δ9-THCA helped reduce their weight and improve their blood sugar control. It also drastically lessened their liver damage and immune cell count.
In conclusion, the study suggests that Δ9-THCA could help prevent liver damage and manage fatty liver disease, and this warrants more research.
Cannabinoids and Chronic Liver Diseases
https://pubmed.ncbi.nlm.nih.gov/36012687/
The document titled “Cannabinoids and Chronic Liver Diseases” was published in 2022. It is a comprehensive review that explores the role of the endocannabinoid system (eCBS) and cannabinoids, like CBD and cannabis, in chronic liver diseases (CLDs).
The study is structured around a review of existing literature and research on the topic. It includes data from various studies, including cross-sectional data from the National Health and Nutrition Examination Surveys involving 319,514 adults 18 years and older, and a population-based 3-year prospective study involving 43,093 adults aged 18 years or older.
The study found that among alcohol users, cannabis use was associated with significantly lower odds of developing alcoholic steatosis. In a population-based study, an inverse association was found between cannabis use and obesity. In another study involving 3706 chronically HBV-infected individuals, cannabis use was associated with lower risks of obesity.
In terms of the effects of cannabinoids on chronic liver diseases, the study found that cannabis use or cannabinoid-containing medicines improve the retention and virological outcomes in patients treated for HCV. It also found that cannabis users presented significantly lower fatty liver index scores, accompanied by less frequent liver steatosis, and a lower weight, body-mass index, total cholesterol, and low-density lipoprotein cholesterol compared with non-cannabis users.
In conclusion, the document suggests that cannabinoids may have potential therapeutic benefits for the treatment of chronic liver diseases, but more research is needed to confirm these findings.
Role of cannabis in digestive disorders
https://pubmed.ncbi.nlm.nih.gov/27792038/
The document titled “Role of cannabis in digestive disorders” was published in 2017. It is a comprehensive review that explores the role of cannabis in various digestive disorders, including its effects on the liver.
The study is structured around a review of existing literature and research on the topic. It includes data from various studies, including cross-sectional data from the National Surveys on Drug Use and Health and a study involving 22 patients (10 with IBS, 12 healthy volunteers).
The study found that cannabis has various effects on digestive disorders. For instance, it mentions that cannabis use was associated with significantly lower odds of developing alcoholic steatosis, a type of fatty liver disease. In a population-based study, an inverse association was found between cannabis use and obesity.
Regarding the effects of CBD or cannabis on the liver, the study mentions that modest cannabis use during Hepatitis C virus (HCV) treatment improved treatment outcomes. It also found that cannabis use was associated with a lower prevalence of nonalcoholic fatty liver disease (NAFLD) among patients who are obese.
However, the study also emphasizes that the results have been variable, which could be due to variations in the dose, timing, and type of agent used. It concludes by stating that more research is needed to fully understand the effects of cannabis on digestive disorders and to establish its safety and efficacy as a treatment.
Cannabis in liver disorders: a friend or a foe?
https://pubmed.ncbi.nlm.nih.gov/30169449/
The document titled “Cannabis in liver disorders” was published in 2018. It is a comprehensive review of the effects of cannabis, particularly its constituents cannabidiol and tetrahydrocannabinol, on liver diseases. The study is based on the analysis of available data and key findings from both preclinical and clinical studies.
The study does not involve a specific number of participants or a controlled experiment. Instead, it is a literature review that summarizes and evaluates the findings of other studies. The authors have attempted to provide a detailed understanding of the effects of cannabis on the liver, focusing on the potential therapeutic applications of cannabis and its constituents in the management of liver diseases.
The study found that cannabinoids, such as cannabidiol and tetrahydrocannabinol, have shown anti-inflammatory, antioxidant, and hepatoprotective effects in both in vitro and clinical studies. These effects appear to have potential in the symptom management and treatment of various liver diseases that were previously considered difficult to manage conservatively. For instance, one study mentioned in the review found that daily cannabis use was associated with a reduced prevalence of steatosis (fatty change) in HIV and Hepatitis C coinfected patients.
CBD Alleviates Liver Injuries in Alcoholics With High-Fat High-Cholesterol Diet Through Regulating NLRP3 Inflammasome-Pyroptosis Pathway
https://pubmed.ncbi.nlm.nih.gov/34630100/
The document titled “CBD Alleviates Liver Injuries in Alcoholics” was published in 2021. It is a scientific study that investigates the effects of Cannabidiol (CBD), a component extracted from marijuana plants, on liver injuries induced by a diet high in ethanol and fat (EHFD).
The study was conducted on mice, which were divided into three groups: a control group, an EHFD group, and an EHFD + CBD group. The control group was given a standard diet, the EHFD group was given a diet high in fat and cholesterol supplemented with alcohol, and the EHFD + CBD group was given the same diet as the EHFD group but also received CBD treatment.
The results of the study showed that CBD had a beneficial effect in preventing liver injury induced by the EHFD diet. Specifically, CBD reduced lipid accumulation, liver injury, and oxidative stress induced by the EHFD diet. It also attenuated inflammation by suppressing the activation of NF-κB and the NLRP3 inflammasome, and it inhibited the formation of cleaved GSDMD, a protein associated with inflammation and cell death.
The study found that the levels of triglycerides (TG) and total cholesterol (TC) in the liver increased in the EHFD group, indicating the development of steatohepatitis (a type of fatty liver disease) and liver cell damage. However, CBD treatment significantly inhibited hepatic steatohepatitis and liver injury.
In terms of numbers, the study found that the serum ALT and AST levels, which are indicators of liver damage, were significantly increased in the EHFD group. However, CBD treatment significantly reduced these levels, indicating a reduction in liver damage.
How to Shop for CBD for Liver Damage
When it comes to choosing a CBD product for liver damage, you want to pick something that suits your needs and can effectively support your liver health. Here’s how each of the essential factors might be beneficial for liver damage:
Form of CBD Products
CBD Oil
CBD oil is a commonly recommended form for liver damage due to its quick absorption and easy dosing. Its sublingual administration (under the tongue) ensures rapid delivery to the bloodstream, providing quick relief to the liver. Moreover, the possibility of microdosing allows for a controlled and consistent amount of CBD, which is crucial for maintaining liver health.
CBD Gummies
CBD gummies could be a suitable choice for those who prefer a tasty, slow-releasing form of CBD. While they may take longer to take effect than oils, their long-lasting nature could provide sustained support for liver health over a 4-6 hour period.
CBD Capsules
CBD capsules provide a no-mess, easy-to-take form of CBD. They may not act as quickly as CBD oil, but for those who prefer a familiar method of intake akin to conventional medication, capsules could be a good choice.
Types of CBD
CBD Isolate
CBD isolate might be a suitable choice for those with liver damage who want to avoid THC altogether. It contains pure CBD, with potential therapeutic benefits including anti-inflammatory properties which could support liver health.
Full-Spectrum CBD
Full-spectrum CBD oil may offer enhanced benefits for liver damage due to the ‘entourage effect’, which refers to the potential synergistic interaction of all the compounds in the plant. This might enhance the therapeutic effect, including anti-inflammatory benefits, which are crucial for relieving liver damage.
Broad-Spectrum CBD
Broad-spectrum CBD oil retains most beneficial cannabinoids and compounds except THC. It might be ideal for those who want the potential synergistic benefits of full-spectrum CBD without THC, which is essential for those with liver damage avoiding any potential THC side effects.
Potency of CBD
The choice of potency largely depends on the individual’s condition severity and their response to CBD. Low-potency CBD oil (300 mg) might be useful for general liver health and stress reduction, both crucial for those with liver damage. Mid-potency CBD oil (600 mg) can manage moderate discomfort and inflammation often associated with liver damage. For more severe conditions, high-potency CBD oil (1,000 mg) might be needed to alleviate pain, inflammation, and stress related to liver damage.
Remember, when selecting a CBD product for liver damage, it’s important to consult with a healthcare provider to make an informed decision based on your specific needs and medical condition.
FAQ
Is CBD safe for your liver?
In most cases, CBD appears to be safe for the liver when taken in appropriate doses. High doses of CBD may temporarily raise liver enzymes, indicating stress or inflammation. However, this effect seems to be transient. More research is still needed on CBD’s long-term impact on the liver.
Does CBD damage the liver?
There is currently no evidence that CBD directly causes liver damage or liver disease. However, extremely high doses may temporarily raise liver enzymes, indicating possible inflammation. This seems reversible once CBD is stopped or lowered. CBD may interact with some medications metabolized by the liver.
How is CBD processed in the liver?
Like most compounds, CBD is processed and broken down by enzymes in the liver known as cytochrome P450s. One study found CBD can temporarily inhibit these enzymes’ activity, which may alter how other drugs are metabolized. This effect fades as CBD leaves the body.
What dose of CBD could affect the liver?
Doses over 200mg per day seem more likely to temporarily raise liver enzymes in some people. However, even high doses up to 1500mg per day have not caused toxicity in studies. It is unclear what long-term dose may negatively impact the liver. Start with low doses.
Can CBD help liver disease?
Early research suggests CBD may protect the liver from damage and even promote healing. This seems related to its antioxidant and anti-inflammatory properties. More studies are underway examining CBD’s potential benefits for certain liver conditions like non-alcoholic fatty liver disease.
Should you take CBD with liver medications?
You can take CBD with liver medications, but check for interactions first. CBD can inhibit enzymes that metabolize many medications passed through the liver. Your doctor may monitor liver enzymes and adjust medication levels as needed if combining CBD with liver meds.
Does CBD treat liver cancer?
There is preliminary evidence CBD may slow or prevent the spread of certain types of liver cancer cells. However, human trials are still lacking. CBD is not a proven treatment for any type of liver cancer yet but may help with symptoms and side effects alongside standard care.
Can CBD worsen liver problems?
In rare cases, CBD could potentially exacerbate existing liver disease according to some doctors. Those with compromised liver function may want to use lower doses of CBD and monitor for any increase in liver enzymes. Discuss CBD use with your hepatologist.
Should you avoid CBD with liver issues?
You do not necessarily need to avoid CBD if you have liver issues. However, discuss it with your doctor and closely monitor liver enzymes and function. Lower CBD doses and shorter treatment durations are safer if concerned about effects on the liver.
Does CBD help hepatitis?
A few early studies indicate CBD may benefit those with viral hepatitis. CBD may reduce inflammation and slow fibrosis progression. However, research is extremely limited. CBD should not replace standard antiviral medications for hepatitis. More human studies are needed.